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New studies have linked marijuana use with heart disease. In particular, one study, published in "Molecular Psychiatry", suggests that heavy marijuana use (smoking at least one joint of marijuana per day) causes triglycerides, a type of fat found in the blood, to increase. An overabundance of triglycerides causes the body's blood vessels to clog, which can eventually precipitate a heart attack.
Another fairly recent study suggests that marijuana use affects the hearts of recreational users as well. A Harvard University study in 2000, which surveyed roughly 4,000 people who suffered heart attacks, found that about 37 out of the 124 marijuana users suffered a heart attack within one day of using marijuana. One leader of the study, Dr. Murray Mittleman, believes these people had heart attacks because the average person's heart rate jumps to about 40 beats more per minute after using the drug. This finding led researchers to conclude that the average person's risk for heart attack is about five times higher after smoking marijuana, namely the first hour after smoking it.
Other researchers argue that using marijuana causes insignificant risks to the cardiovascular system. Notably, Dr. Lester Grinspoon, a marijuana researcher at Harvard University, believes that marijuana does not directly correlate with cardiovascular disease. He specifically referred to the Harvard study, claiming that marijuana causes the heart to jump 20 beats, rather than 40 beats, more per minute. In any case, marijuana's correlation with heart disease remains unresolved.

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