Turn Delta 9 into Delta 10?

[Governor]

I've heard there is a technique that increases Delta 9 effects by 2000% and changes it's structure to Delta 10.

Anyone?

[deadhead94]

I don't know, but if there is a way to make 11-OH-THC do that....it is 3x as strong and 2x as potent smoked........but 3x less potent orally

[Koery]

Never know there might be a drug much better than weed. Perhaps on another planet or from a rare Algae or Kelp deep, deep in the ocean. Just Imagine,
"Scientists and Deep-ocean going vessels have just discovered a rare form of ocean algae containing MTHC, a potent chemical determined to be three thousand times more potent that current THC>"

[Governor]

ooooooooooooh yeah!

[koshiva]

I am not sure, but are you refering to THC isomerization? If so heres a link among many http://nepenthes.lycaeum.org/Drugs/THC/isomerize.html

I have read conflicting reports regarding this, some say it doesn't work. But who knows how many things you could try to do with oil...to modify the thc some how.

[slunt]

Anyone ever come up with an answer?

[Captain Cannabis]

what kind of lab equipment do you have

[Pharm Girl]

I found these references:


Apparently some methods of preparation even alter the chemical makeup of the herbal material you are processing - converting some cannabinoids into higher-level ones even (eg. delta-9 THC being converted into delta-10 and even delta-11 THC). Higher level cannabinoids can be much more potent than lower ones. So your best bet may be to soak a bud in your favorite booze or gently simmer in butter or oil. From there, you can do whatever you want - add the alcohol to whatever drink you like, or cook/bake with the butter or oil. If you're into the coffee idea, you might be able to incorporate ganja and coffee cream or high-fat milk I suppose.

Toronto Hemp Company (THC) - Information - T.H.C.'s F.A.Q. - Hemp Marijuana Cannabis Store/Shop and Resource Centre / Center

Also since the dutch started to enhance the cannabis plant it's level of Delta 10 THC is very high. So high that to the inexperienced it's too strong. They are best off using hasish instead of weed.

Receipe for turning bad hasish to good hasish, disolve in alcohol for a couple of weeks. Filter. Heat the resin to 180 celsius for 15 minutes. This well turn low delta thc into high delta thc

[Captain Cannabis]

i dont understand the high/low designation. the number doesn't mean one is better or worse than another, it tells you about the connectivity of the chain only. it also dependings on which numbering system you are using (IUPAC/non-IUPAC numberings are different). associating subtle nomenclature variances with potency is silly because it doesn't mean anything. the range of activity of structurally related molecules is quite large. it varies from biologically inactive in some to a total duration of 36-48 hours in others.

[Captain Cannabis]

http://www.nida.nih.gov/pdf/monographs/79.pdf

http://www.druglibrary.org/olsen/DEA/shulgin.html

[slunt]

I know that heating"RAW" marijuana to about 375 degrees Fahrenheit causes maximum molecular activity and provides the most combined THC molecules, which is of course why cooking with pot is so much more powerful than smoking it, but refining and changing molecular structure to make the cannabinoid molecule stronger and more potent seems a little beyond your common man on the streets technical ability. THC extraction is one thing, but changing it's molecular structure seems a bit of a reach.
I know that scientist can change chemical potency, but the question remains how.
It is noteworthy that, within the structural constraints present in the THC ring
system, changing the position of the double bond in the alicyclic ring, the length
and branching of the side chain, or producing hydroxy metabolites at the 11- or
8-positions do not alter qualitatively the THC effects but may strongly affect
potency. Changing the double bond from delta-9- to delta-8- or delta-6areduces
potency. Decreasing the length of the side chain by two carbons reduces
potency by 75%. Increasing the length of the side chain with branching enhances
potency several fold. Substitution of a hydroxyl group in the 11-position retains
potency, while hydroxylation in the 8-position reduces potency by 80%.

[hempophiliac]

It's obvious I majored in the wrong things in college. Of course I was smoking a fair amount of weed in those days, so maybe it would have made no difference! Keep discussing, and I'll do my best to keep up. It's a very intriguing notion.

[Captain Cannabis]

Originally Posted by slunt

I know that scientist can change chemical potency, but the question remains how.

i study organic chemistry if you are actually interesting you are going to need a well supplied lab. it would also be helpful to have access to an nmr spectrometer to make sure you are doing the right things.

[hempophiliac]

Hmmm...I took a couple courses of inorganic chemistry as an undergrad at Michigan State 30+ years ago, and chances are half of what I learned back then was wrong, anyway!
Even so, if you all gain insight into the mysteries of the universe, or weed, feel free to post them. I'll gladly read them and feel hope for an interesting future.