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Old 05-19-2006, 08:37 PM   #1 (permalink)
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placebo effect of smoking.

I have eaten marijuana before, right now since i cant smoke it's my perfered method, i know the high is nowhere near simular of smoking it, not only is it more potent, but almost an entirely different high all together.

that has always stuck in me the question of just whether or not smoking it really produces any high at all, and that maybe it's just the placebo of the expanding lungs and cut off of oxygen that really produces the high, not so much the delta-THC stuff... even if it is, it's just a very faint minute effect of the drug.

always wanted to get peoples feedback on their thoughts about this, however i know i'll get crucified if i post this in any other forum.

so what do you think, is marijuana mostly placebo when engaged in the act of smoking it?

are we really just getting high on some expensive carbon monoxide?
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The most dangerous drug on this planet has to be oxygen.

A gateway drug to say the least, further more people use without even consideration, not consenting to moderation in the least, and dont even get me started on the withdrawels.


the goal of alchemy is to turn lead into gold. to take a substance and combine it with another substance that makes it more than it's origenal worth. in this sense, you really need to start making bronze statues of your pharmacist or local chemist, for they have made gods own medicine, morphine, and in contrast, a shiney rock doesnt seem to compete.
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Old 05-19-2006, 08:55 PM   #2 (permalink)
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you need to smoke some better pot, mang.


give me a month or two.

sativas to show you teh light.
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Old 05-19-2006, 09:03 PM   #3 (permalink)
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dont get me wrong, there is high or a pleasant effect to smoking it.

i've grown some nice indicas and sativas in my life before and happily smoked them.

it's just that its nowhere near the effect of eating it, not only in potency, but also just how it feels.

it's almost like a entirely different drug to me.
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The most dangerous drug on this planet has to be oxygen.

A gateway drug to say the least, further more people use without even consideration, not consenting to moderation in the least, and dont even get me started on the withdrawels.


the goal of alchemy is to turn lead into gold. to take a substance and combine it with another substance that makes it more than it's origenal worth. in this sense, you really need to start making bronze statues of your pharmacist or local chemist, for they have made gods own medicine, morphine, and in contrast, a shiney rock doesnt seem to compete.
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Old 05-20-2006, 12:02 AM   #4 (permalink)
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Just think about the effects of smoking cigs or other herbs.
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woods > vanilla
Kishar steals his aunt's morphine patches because he has the moral sense of George Bush

Prisons are built with stones of Law. Brothels with bricks of religion.
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Old 05-20-2006, 12:58 AM   #5 (permalink)
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well actually ciggarettes are a big part of my doubt of marijuana's smokable high.

while chewing on a piece of nicotine gum, you still feel somewhat of the presence of tobacco's high, it's may not be cool and refreshing, but the presence is still simular and eventually the relaxation comes all the same.

that is not the way with weed.

weed has a entirely different presence eaten, a presence that almost overshadows a oxycontin nod (in my experience), which just leads me wondering how little we get through lining of our lungs.

as cliche as it sounds, weed is actually a pretty strong drug, something i dont think alot of people are even aware about.

it may be a paranoid delusion, but sometimes i actually wonder if propaganda somehow purposely steered the baby boomers to smoking it in hopes that they wouldnt know it's full potential.

but yeah, that's me, im kinda of paranoid like that.
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The most dangerous drug on this planet has to be oxygen.

A gateway drug to say the least, further more people use without even consideration, not consenting to moderation in the least, and dont even get me started on the withdrawels.


the goal of alchemy is to turn lead into gold. to take a substance and combine it with another substance that makes it more than it's origenal worth. in this sense, you really need to start making bronze statues of your pharmacist or local chemist, for they have made gods own medicine, morphine, and in contrast, a shiney rock doesnt seem to compete.
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Old 05-20-2006, 01:52 AM   #6 (permalink)
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Different drugs have different effects when taken through different routes, even in the same class of drugs. Look at methadone and heroin comparing oral and injection dosing. They're close to the same with methadone, but opposite ends of the spectrum with heroin.
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Originally Posted by meheh
woods > vanilla
Kishar steals his aunt's morphine patches because he has the moral sense of George Bush

Prisons are built with stones of Law. Brothels with bricks of religion.
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Old 05-20-2006, 11:42 PM   #7 (permalink)
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Smile

I don't know man. I don't think the 'placebo affect' plays a large role in getting high smoking a joint. The mere fact that some strains get you high or different highs (indica/sativa) makes it way less likely.

That being said, eating it certainly does produce an entirely different high. I don't eat it very often, and a few weeks ago I decided to have ALOT of really good herb in a batch of brownies. I have never been so 'high', mixed with a few beers and a joint, needless to say I was gone!
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Old 05-21-2006, 03:54 AM   #8 (permalink)
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its a matter of chemistry

when delta-9-tetrahydrocannabinol is prepared for eating, it is converted to 11-hydroxy-delta-9-tetrahydrocannabinol , which is a harder chemical for your body to process, and thus requires a larger dose for noticeable effects. the 11-hydroxy-delta-9-thc also exhibits greater effects, explaining why you feel completly stoned out of your head

when you cook with marijuana you are preparing an analogue to the delta-9-thc and making a new molecule, hence why it acts differently on your brain when ingested

when i was doing a bit of research for this post i came across a website that speaks of analogues of delta-9-thc and their reactivity. http://designer-drugs.com/pte/12.162.../chapter2.html

there is a lot of analogues that have never been tested on humans, and an infinite amount of analogues can be created by altering certain functional groups. its interesting that some of them can act for as long as 7 to 10 days, and some permutations completly destroy activity
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Old 05-21-2006, 04:52 AM   #9 (permalink)
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There are a near infinite number of analogues of any drug, but more you test, the greater the percentage will fail to be psychoactive un humans, for two reasons.

First, With a bit of knowledge about biochemistry and some specific knowledge of THC and its relate compounds, isomers, analogues, and the like, you can predict with a fair bit of certainty which compounds I’m msteardmtikiikikivwi ll be psychotropic, and which ones will not. jlo, you might wat rtiun momvljppp cheats.
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Originally Posted by meheh
woods > vanilla
Kishar steals his aunt's morphine patches because he has the moral sense of George Bush

Prisons are built with stones of Law. Brothels with bricks of religion.
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Old 05-21-2006, 05:09 AM   #10 (permalink)
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Quote:
Originally Posted by Woods
...you can predict with a fair bit of certainty which compounds I’m msteardmtikiikikivwi ll be psychotropic, and which ones will not. jlo, you might wat rtiun momvljppp cheats.
What kind of encoding is this
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...America isn't perfect, but look at all those other countries out there with no social assistant programs. We are leading the way, everyday I look out my window and see homeless people digging through my trash...
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