artificial cannabinoids, HU210, Spice, Genie, Yucatan Fire

kitch · 06-26-2009, 06:01 PM

Quote:

March 2009

- INTELLIGENCE ALERT -

“SPICE” - PLANT MATERIAL(S) LACED WITH SYNTHETIC
CANNABINOIDS OR CANNABINOID MIMICKING COMPOUNDS

Photo 1 - Packages are about 2x3 inches.
The Customs and Border Protection (CBP) - Chicago Laboratory (Illinois) recently received five small, resealable, bright foil packets containing dull olive-colored plant material(s), labelled as “Spice Gold,” “Spice Silver,” “Spice Diamond,” “Genie,” and “Yucatan Fire” incense (see Photo 1, right, and Photos 2 - 3, next page), all reputedly laced with various synthetic cannabinoids or synthetic cannabinoid mimicking compounds, notably “HU-210” [(6aR,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol); see Figure 1, next page]. The exhibits were selected from a shipment containing approximately 1,500 such packets that were detained by a CBP agricultural specialist at an express parcel service hub in Wilmington, Ohio. The items were not smuggled but were rather part of a formal entry. Standard marijuana analyses (microscopy) of the materials were negative. Analysis of extracts by GC/MS in the scan mode with split injection indicated only the presence of a large amount of vitamin E and other, smaller amounts of various natural products. However, when the extracts were derivatized with N,O-bis(trimethylsilyl)a cetamide and injected splitless with selected ion monitoring, HU-210 was found in very small but verifiable amounts in every packet (not quantitated). The results were confirmed against a standard. These were the first such submissions to the laboratory.

Photo 1 - Packages are about 2x3 inches.
[Additional Laboratory and Editor’s Notes: In addition to the above-named products, there are at least two other such herbal products: “Skunk,” and “Sence.” These products are currently being encountered nationwide. They, and the synthetic cannabinoids and cannabinoid mimic compounds they contain, are also the subjects of widespread discussion and speculation on the Internet. Based on anecdotal reports, HU-210 is hundreds of times more potent than THC; thus, the trace amounts detected in the above case are physiologically active, and these materials may be viewed as “stealth marijuana.” The reference standard of HU-210 used in this case was purchased from Cayman Chemical of Ann Arbor, Michigan. The ions selected for the analysis were m/z 446 (100%), 530 (molecular ion), 447, 474, and 356. Note that HU-210 is named in several different ways; for example: (6aR,10aR)-3-(1,1'-dimethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-6H-dibenzo[b,d]pyran-9-methanol. HU-210 is controlled (Schedule I) in the U.S. (See: HU-210 - [(6aR,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c] chromen-1-ol)]), and products containing it and similar cannabinoids are controlled within the U.S. and in a number of other countries, including Austria, Canada, Germany, the Netherlands, and Switzerland. In addition to HU-210, there are at least half a dozen other compounds with similar structures, plus several unrelated compounds that have cannabinoid mimicking effects (notably JWH- 018 (1-pentyl-3-(1-naphthoyl)indole)), that are being used to adulterate the plant materials in “Spice” and similar products. An article presenting mass spectral data and background information on these compounds was recently published on line (not yet published in hard copy); see: Auwarter V, Dresen S, Weinmann W, Muller M, Putz M, Ferreiros N. “Spice” and other herbal blends: Harmless incense or cannabinoid designer drugs? Journal of Mass Spectrometry 2009.]

So I learned a long time ago to completely write off any weed 'alternative' since they're pretty much all bullshit. This however caught my eye. Does anyone know where these compounds are being produced? I suspect Canada or England has a loophole allowing such things, since the package is in English. Has anyone tried any product they know to contain HU-210 or any other artificial cannabinoid?

**Kompressor** · 06-26-2009, 06:05 PM

I thought Spice Gold was produced in the mideast somewhere.

kitch · 06-26-2009, 06:10 PM

well I did a little more research and found wikipedia-spice

Seems like by and large these products aren't regulated. They don't show up on a standard THC panel and appear to be widely available in more liberal nations. Apparently the ingredients list is pure fiction. Has anyone tried any of them though?

kitch · 06-26-2009, 06:15 PM

If anyone has clearance to order Schedule 1 drugs in the US you can get HU-210 here:

Cayman Chemical | HU-210 (DEA Schedule I Regulated Compound) | Description (CAS 112830-95-2)

what a dream...

al-Mu'akhkhir · 06-27-2009, 01:00 AM

Spice is legit.

It's more expensive than real weed though, and apparently it's become illegal in most of north america, or something, I know EDIT wasn't shipping it as of about 6 months ago to N.A.

06-26-2009, 06:05 PM	#2 (permalink)
Kompressor Voice of Reason Join Date: Dec 2000 Location: Illinois Posts: 8,066 Thanks: 0 Thanked 2,849 Times in 1,509 Posts	I thought Spice Gold was produced in the mideast somewhere. __________________ Think like a man of action, act like a man of thought. -H. Bergson

06-27-2009, 01:00 AM	#5 (permalink)
al-Mu'akhkhir Vem Para Ficar Join Date: Jun 2006 Location: in some pussy Posts: 3,265 Thanks: 500 Thanked 351 Times in 270 Posts	Spice is legit. It's more expensive than real weed though, and apparently it's become illegal in most of north america, or something, I know EDIT wasn't shipping it as of about 6 months ago to N.A. __________________

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